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Dovitinib Dilactic Acid
CAS No. 852433-84-2
Dovitinib Dilactic Acid( Dovitinib Dilactic acid | TKI258 Dilactic acid | CHIR-258, TKI258 )
Catalog No. M17618 CAS No. 852433-84-2
Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 68 | Get Quote |
|
| 10MG | 103 | Get Quote |
|
| 25MG | 211 | Get Quote |
|
| 50MG | 365 | Get Quote |
|
| 100MG | 583 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDovitinib Dilactic Acid
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NoteResearch use only, not for human use.
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Brief DescriptionDovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor.
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DescriptionDovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
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In Vitro——
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In Vivo——
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SynonymsDovitinib Dilactic acid | TKI258 Dilactic acid | CHIR-258, TKI258
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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Recptorc-Kit| FGFR1| FGFR3| FLT3| VEGFR3/FLT4
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number852433-84-2
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Formula Weight572.59
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Molecular FormulaC21H21FN6O·2C3H6O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 30 mg/mL (52.39 mM)
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SMILESCC(C(=O)O)O.CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N/C(=C/4\C(=C5C(=NC4=O)C=CC=C5F)N)/N3
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Chemical Name2-Hydroxypropanoic acid compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1- piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Trudel S, et al. Blood. 2005, 105(7), 2941-2948.
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